hdac6 degrader-1 — TargetMol Chemicals

Cat No.	Product Name	Targets
T77922	HDAC6 degrader-1	PROTACs
	HDAC6 degrader-1, a proteolysis-targeting chimeric molecule (PROTAC), incorporates the selective HDAC6 inhibitor Nexturastat A (Nex A) for HDAC6 binding, a linker, and an E3 ligase recruiting ligand. This compound effect...	PROTACs
T69753	HDAC6 degrader 9c	HDAC
	HDAC6 degrader 9c is a small molecule histone deacetylase 6 (HDAC6) degrader that can be used to study cancer or other diseases.	HDAC
T75017	PROTAC HDAC6 degrader 1
	Compound A6, a potent and selective PROTAC HDAC6 degrader, exhibits a DC50 of 3.5 nM. It demonstrates notable antiproliferative activity by inducing apoptosis in myeloid leukemia cell lines [1].
T81392	PRO-HD3	HDAC
	PRO-HD3 is a cell-specific, PROTAC-based degrader targeting HDAC6 [1].	HDAC
T81393	PRO-HD2	HDAC
	PRO-HD2 is a selective, PROTAC-based degrader of HDAC6 [1].	HDAC
T81394	PRO-HD1	HDAC
	PRO-HD1, a PROTAC (proteolysis-targeting chimera) HDAC6 degrader, effectively degrades HDAC6 in A549 cells and inhibits Jurkat cell proliferation with an IC50 of 5.8 µM [1].	HDAC
T75018	HDAC6 degrader-3	PROTACs
	HDAC6 degrader-3, a selective and potent degrader of HDAC6 through ternary complex formation and the ubiquitin-proteasome pathway, exhibits a DC50 value of 19.4 nM. With IC50 values of 4.54 nM for HDAC6 and 0.647 μM for ...	PROTACs